According to Marketwatch.com (a business and investment website run by the Wall Street Journal), Minneapolis “far and away, remains where it's at for business.”

Last year, the Twin Cities was at the top of MarketWatch's list in the first annual survey of where companies tend to gravitate and create the most jobs. It appears little has changed for the region, as the concentration of companies has stayed strong, and job growth continues while unemployment remains relatively low.

The Twin Cities area has a baker's dozen of public and private firms with sales of more than $10 billion, up from 12 a year ago. But the region also is friendly to small business, as it garnered the top ranking among all metro areas in that category.
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Many of the region's companies are home-grown and have thrived in the environment. UnitedHealth, for example, was started in 1974 and now boasts $80 billion in annual sales.
Other companies have deeper roots, such as Traveler's in St. Paul, which got its start in 1853. It's been sustained in part by a highly ranked school system and the network of higher-education providers in the region.

"It's a very educated workforce," said Andy Bessette, Traveler's chief administrative officer. "The people here, the school systems, are very good."